Get Control of Seasonal Allergies with the Best Anti-Allergen Spray
Tackle allergens head-on with the best anti-allergen spray to keep dust mites and pet dander at bay. Whether you're battling seasonal allergies or striving for better air quality, these sprays to reduce allergens in the home are versatile and effective.
Ideal for use on furniture, mattresses, drapes, carpets, and even laundry, they target allergens where they settle. While these allergy sprays for house use work wonders on surfaces and fabrics, pairing them with an air purifier can maximize results, especially in urban areas with high pollution levels.
Our 2025 Guide to the Best Anti Allergen Sprays includes:
How to get rid of dust mites
Natural and organic allergy sprays
Carpet spray for dust and pet dander
Instead of choosing one or the other, combine the sprays with air purifiers and you’ll be able to breathe easy.
1. Allertech
Type of Anti-Allergy Spray | Non-toxic Allergen Solution
Anti-Allergy Bedding Benefits | Eco-Friendly, Fair Trade, Organic, GOTS Certified, Recyclable, Give Back, Socially Responsible, Made in the USA, Green
Our first review is of the Allertech Allergen solution. This spray is an excellent option for people who are sensitive to the chemicals you might find in common allergy sprays as it uses a plant and mineral-based formula. Since it’s non-toxic, it’s perfect to use on almost every surface and even safe to spray on pet bedding.
How effective is it? Independent lab tests have found that it definitely reduces all of the standard allergens such as dander, mites and pollen. If you’re sensitive to scents, keep in mind that this does have a smell, although it’s quite subtle.
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2. Allersearch
Type of Anti-Allergy Spray | Oxidizing Allergen Solution
Anti-Allergy Bedding Benefits | Eco-Friendly, Fair Trade, Organic, GOTS Certified, Recyclable, Give Back, Socially Responsible, Made in the USA, Green
Our next review is of the Allersearch Anti-Allergen spray. This spray uses a patented oxidizing formula that destroys the most common allergens such as mites, dander, pollen and mold. It does not contain any tannic acid or other chemical, which means you can use it on any type and color of fabric without having to worry about unseemly stains.
Since it doesn’t use any harmful chemicals, you can use the spray on your and your pet’s bedding. Just spray on the surfaces you want to treat and then vacuum the area to remove the allergens. The spray won’t permanently get rid of allergens, but you’ll only have to do treatments every month, which is a small price to pay for clean air.
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3. Allergy Asthma Clean
Type of Anti-Allergy Spray | Mineral Allergen Solution
Anti-Allergy Bedding Benefits | Eco-Friendly, Fair Trade, Organic, GOTS Certified, Recyclable, Give Back, Socially Responsible, Made in the USA, Green
If you suffer from asthma and allergies, then you’ll want to check out our review of the Allergy Asthma Clean. As the name suggests, this spray not only gets rid of standard allergens, it also targets asthma triggers such as cockroach allergens. Unlike other sprays, this one comes with just the minerals, so you’ll have to top it off with water in order to use it.
Once you’ve mixed the water and the minerals together, you can use it on everything. You can even spray it in the air to reduce air borne allergens. The minerals then attract and attach to allergen molecules and proteins and neutralizes them. Does it work? Independent tests find that it is able to reduce 93 percent of pet dander, mites and cockroach allergens.
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4. Allerpet
Type of Anti-Allergy Spray | Dog Allergen Solution
Anti-Allergy Bedding Benefits | Eco-Friendly, Fair Trade, Organic, GOTS Certified, Recyclable, Give Back, Socially Responsible, Made in the USA, Green
Dog allergies affect 10 percent of the worldwide population. If you fall into that 10 percent, then you’ll want to look at our review of Allerpet. As much as you might love your pooch, it can be difficult to live with them, especially if you have allergies. Sure, you can give them a bath, but it’s messy and not all dogs love getting bathed!
Enter Allerpet. This spray has been recommended by vets and allergists for years as a great way to combat dog allergies. It’s completely non-toxic and fragrance-free, making it completely safe for you and your dog. It’s also clinically proven to reduce dander in homes by around 50 percent. All you need to do is spray some Allerpet onto the provided mit and rub down your dog once a week for best results.
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5. PUREFY
Type of Anti-Allergy Spray | Asthma and Allergen Solution
Anti-Allergy Bedding Benefits | Eco-Friendly, Fair Trade, Organic, GOTS Certified, Recyclable, Give Back, Socially Responsible, Made in the USA, Green
Up next is our review of Purefy’s anti-allergy spray. As the name suggests, the spray not only purifies your home of allergens, it’s also hypoallergenic and made from non-toxic ingredients. You also won’t have to worry about any unnecessary fragrances or chemicals.
As it doesn’t use any harsh chemicals or acids, you can spray it on pretty much every surface. Heck, you can spray it in the air as well. The spray itself is very fine, leading to excellent coverage so you don’t have to use a lot of product to get great results.
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6. LivePure
Type of Anti-Allergy Spray | Plant-based Allergen Solution
Anti-Allergy Bedding Benefits | Eco-Friendly, Fair Trade, Organic, GOTS Certified, Recyclable, Give Back, Socially Responsible, Made in the USA, Green
Our next review is of LivePure anti-allergy spray. You can use the solution in multiple ways. Yes, you can spray it on your carpet, furniture and bedding, but you can also use ½ cup in a load of laundry or mix it in with your carpet shampoo for a deep cleaning.
The spray uses a plant-based formula so it’s gentle on all types of fabrics and will not stain. It’s also chemical-free and free of fragrance. All of that doesn’t matter if it doesn’t work, of course, Luckily, it neutralizes 97 percent of common allergens.
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7. The Ecology Works
Type of Anti-Allergy Spray | Clean Allergen Solution
Anti-Allergy Bedding Benefits | Eco-Friendly, Fair Trade, Organic, GOTS Certified, Recyclable, Give Back, Socially Responsible, Made in the USA, Green
Up next is our review of EcologyWorks Anti-Allergen solution. Sure, it might not sound fancy, but it does exactly as the label advertises. The plant and mineral-based formula is eco-friendly and non-toxic so you can use it everywhere in your house. It’s great for any surface and, as it doesn’t contain any harmful chemicals, is great even for people with sensitive skin.
The spray uses a plant-based formula and is 100 percent biodegradable. While it will neutralize allergens such as dust mites and pollen, it isn’t as effective on pet dander. So if you have someone who is highly allergic to dogs or cats, they will still have to take a daily allergy pill to control their body’s reaction.
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8. Easy Air
Type of Anti-Allergy Spray | All Natural Allergen Solution
Anti-Allergy Bedding Benefits | Eco-Friendly, Fair Trade, Organic, GOTS Certified, Recyclable, Give Back, Socially Responsible, Made in the USA, Green
You can find anti-allergy sprays that are good for you and the environment. Just check out our review of Easy Air allergy relief spray. This spray contains only natural ingredients and is both eco-friendly and biodegradable. The main focus of the spray is on neutralizing dust mite feces, but it can also neutralize and denature other allergens such as dust, pet dander and so on.
You can safely use the spray on every surface whether hard or fabric. Just remember that while it might work on airborne allergies, it will not work on mold. With that said, it’s a great option for someone who wants to be a bit more green in their allergy spray choice.
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9. Dust-Mitex
Type of Anti-Allergy Spray | Dustmite and Fleas Allergen Solution
Anti-Allergy Bedding Benefits | Eco-Friendly, Fair Trade, Organic, GOTS Certified, Recyclable, Give Back, Socially Responsible, Made in the USA, Green
If you want to get rid of dust mites and fleas, then you’ll want to check out this review of Dust-Mitex. While not an allergy spray per se, it will get rid of both fleas and dust mites, both of which can cause allergies. You can comfortably use it on pet beddings and other fabric surfaces as it does not contain any harsh chemicals or poisons.
What’s great about this spray is that it’s long-lasting. Many other allergy sprays require you to spray every month. Luckily, Dust-Mitex keeps both pests at bay for up to six months thanks to its use of Boron. While it doesn’t deal with other allergens, the fact that you can get rid of dust mites for six months means you are controlling one of the biggest sources of allergic reactions.
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10. Febreze
Type of Anti-Allergy Spray | Odor Eliminator and Allergen Solution
Anti-Allergy Bedding Benefits | Eco-Friendly, Fair Trade, Organic, GOTS Certified, Recyclable, Give Back, Socially Responsible, Made in the USA, Green
If you’re looking for a trusted name in the anti-allergy spray market, you’ll want to read our review of Febreze. No, we’re not talking about the odor spray, although this spray does do that. The Febreze anti-allergy spray both removes odor and inanimate allergens such as pollen, dander and dust mite feces.
You can easily find this spray in your local store, making it a very popular choice. With that said, it might not be great for people who have sensitive skin or noses as it does contain fragrances and they don’t use all natural ingredients. Still, it does the job and is easy to get your hands on so if you need to get rid of your allergies NOW, then you can just head to your local store and pick it up.
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11. CleanSmart
Type of Anti-Allergy Spray | Disinfectant Allergen Solution
Anti-Allergy Bedding Benefits | Eco-Friendly, Fair Trade, Organic, GOTS Certified, Recyclable, Give Back, Socially Responsible, Made in the USA, Green
If you’re looking for something that will get rid of mold and fungus, then you’ll want to read our review of CleanSmart. Although this spray is not technically an anti-allergy spray, it does manage to destroy two major allergens: mold and fungus. As an added bonus it also kills 99.9 percent of bacteria and germs.
You don’t have to be worried about inhaling or ingesting toxins either. The spray uses hypochlorous, a natural disinfectant. It’s perfectly safe to use for food contact on counters and appliances and actually boasts the highest EPA safety rating for food contact surfaces. Since it is non-toxic, it’s also perfectly safe to use around pets and kids.
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12. Puracy
Type of Anti-Allergy Spray | All Purpose Allergen Solution
Anti-Allergy Bedding Benefits | Eco-Friendly, Fair Trade, Organic, GOTS Certified, Recyclable, Give Back, Socially Responsible, Made in the USA, Green
Our next review is of the Puracy All Purpose cleaner. Although it’s not technically an anti-allergy spray, this cleaner can clean up pretty much all of life’s messes from food to grease to pet accidents. It can handle it all and is hypoallergenic itself so you won’t get any allergies from using it around the house.
As you would expect, the spray is made from all natural plan and mineral-based ingredients to create a food-grade solution. It’s free from harsh chemicals and safe to use on every non-porous surfaces. While it doesn’t eliminate allergens, it does make it a lot easier to clean it up around your house!
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13. Easy Air Anti-Allergen
Type of Anti-Allergy Spray | Laundry Rinse Allergen Solution
Anti-Allergy Bedding Benefits | Eco-Friendly, Fair Trade, Organic, GOTS Certified, Recyclable, Give Back, Socially Responsible, Made in the USA, Green
Up next is our review of Easy Air’s anti-allergy laundry solution. As the name suggests, instead of a spray, you add this to your laundry along with your detergent. Together they eliminate the allergens that cling to fabric. Since you’re using it on your clothes and bedding, you’ll be happy to learn that it is made from all natural and 100 percent organic ingredients.
This laundry additive is a perfect option for people who don’t have many fabric surfaces or who want to make sure they get rid of all the allergens in their house. This was specifically made to penetrate cloth fibers in order to fully destroy allergens. Its effectiveness is lab-tested and will definitely become a mainstay in your home.
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14. ProBioCare
Type of Anti-Allergy Spray | Laundry Rinse Allergen Solution
Anti-Allergy Bedding Benefits | Eco-Friendly, Fair Trade, Organic, GOTS Certified, Recyclable, Give Back, Socially Responsible, Made in the USA, Green
Last but not least is our review of Allersearch Allergy Spray. While it might be on the more expensive side, this spray differs from everything else on the list as instead of using a plant or mineral-based solution it uses a probiotics. Yes, the gut bacteria often found in yogurt and fermented foods. While it might be a bacteria, it’s actually not harmful to your health at all and is completely safe to use on washable surfaces, skin and clothing.
Of course, the probiotic used in this spray is a bit different than the one found in yogurt. It uses a proprietary bacterial strain that consumes dust mite waste, dead skin, pet dander, sweat and other organic matter. It also consumes odor-causing organic matter giving it a side benefit of acting as an air freshener.
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Put An End To Seasonal Allergies With Top Rated Anti Allergy Spray For Home
There are many different anti-allergy options on the market for your seasonal allergies. Many of them use natural and non-toxic ingredients so you can safely use them on all of your surfaces. While the sprays are all purpose options, there are other options that might work better on hard surfaces and fabrics. While all of these sprays are lab-tested to be effective against allergens, they won’t necessarily be 100 percent effective. If you have severe allergies, you might want to combine a few different options such as a spray and laundry additive and an air purifier to really keep your air clean. Of course, these aren’t long-term treatments and you’ll generally have to spray down your house around every month to keep the allergens to a minimum.
Lisa Czachowski is a professional social blogger and has worked on several online publications including Citrus Sleep. Lisa is an experienced content writer and copyeditor. You will find many of her works throughout CitrusSleep.com that cover a wide array of subjects including sustainability, natural, sleep products, health, fashion and many more. She is passionate about what providing as much information as possible on products you bring in your home and what we wear.
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