Ready to give your guest room some comfortable upgrades, the guest bed mattresses on this list will help get the job done. This is why we have created a list of mattresses that are perfect for any guest room. We love that these mattresses are designed to be comfortable for all types of sleepers. Plus, we love that all of these mattresses are eco-friendly and safe as well. We know it is important for your guests to not only sleep comfortably, but sleep on a surface that is safe, organic and won’t harm them in any way.